BiologyGrade 9
Cell biology
Diffusion, osmosis, active transport, microscopy, mitosis
Clinical / exam questions → Explain osmosis in plant cells; compare transport mechanismsHigh-yield notes. Question-led.
Full Med with Spence curriculum map for GCSE Science, A-Level Biology, A-Level Chemistry, Medical School OSCE and MRCP Part 1. Each topic is designed to become a colourful premium note sheet, a short teaching video and a linked question set.
GCSE Science
Highest-yield map designed for rapid revision, grade-focused understanding and question-led teaching.
BiologyGrade 8/9
Organisation
Enzymes, digestion, heart, blood vessels, coronary disease
Clinical / exam questions → Interpret enzyme graphs and cardiovascular risk scenariosBiologyGrade 8/9
Infection & response
Pathogens, vaccination, antibiotics, monoclonal antibodies
Clinical / exam questions → Explain immunity and antibiotic resistanceBiologyGrade 8/9
Bioenergetics
Photosynthesis, limiting factors, respiration, oxygen debt
Clinical / exam questions → Analyse limiting-factor graphsBiologyGrade 9
Homeostasis
Nervous system, hormones, glucose, kidney, temperature
Clinical / exam questions → Compare insulin/glucagon and ADH mechanismsChemistryGrade 8/9
Atomic structure & periodic table
Subatomic particles, isotopes, groups, trends
Clinical / exam questions → Calculate relative atomic mass and explain group trendsChemistryGrade 9
Bonding & structure
Ionic, covalent, metallic, nanoparticles, polymers
Clinical / exam questions → Link structure to propertiesChemistryGrade 9
Quantitative chemistry
Moles, concentration, titration, percentage yield
Clinical / exam questions → Multi-step mole calculationsChemistryGrade 8/9
Chemical changes & electrolysis
Reactivity, acids, salts, electrolysis products
Clinical / exam questions → Predict electrolysis products and half-equationsPhysicsGrade 8/9
Energy & electricity
Stores, transfers, circuits, resistance, power
Clinical / exam questions → Calculate efficiency, power and circuit valuesPhysicsGrade 9
Forces & motion
Newton's laws, stopping distances, momentum
Clinical / exam questions → Interpret velocity-time graphsPhysicsGrade 8/9
Waves & electromagnetism
EM spectrum, lenses, magnetic fields, motors
Clinical / exam questions → Explain wave properties and electromagnetic induction
Question bank link: Topic-specific questions are mapped to each note pack. Full question bank coming next.
A-Level Biology
Highest-yield map designed for rapid revision, grade-focused understanding and question-led teaching.
CoreA*
Biological molecules
Carbohydrates, lipids, proteins, enzymes, DNA, ATP, water
Clinical / exam questions → Use structure-function language in mark schemesCoreA*
Cells & immunity
Cell structure, membranes, mitosis, immunity, antibodies
Clinical / exam questions → Explain immune response and membrane transportCoreA*
Exchange & mass transport
Gas exchange, digestion, heart, cardiac cycle, haemoglobin
Clinical / exam questions → Link pressure, valves and flow in the cardiac cycleCoreA*
Genetics & protein synthesis
DNA replication, transcription, translation, mutations
Clinical / exam questions → Predict effects of gene mutationsCoreA*
Energy transfers
Photosynthesis, respiration, ATP, limiting factors
Clinical / exam questions → Interpret biochemical pathways and graphsCoreA*
Response & homeostasis
Nervous coordination, hormones, muscles, kidneys
Clinical / exam questions → Compare negative feedback loopsCoreA*
Genetics, populations & evolution
Inheritance, Hardy-Weinberg, selection, speciation
Clinical / exam questions → Use chi-squared/Hardy-Weinberg calculationsCoreA*
Gene expression & technology
Epigenetics, recombinant DNA, PCR, electrophoresis
Clinical / exam questions → Explain gene technologies stepwise
Question bank link: Topic-specific questions are mapped to each note pack. Full question bank coming next.
A-Level Chemistry
Highest-yield map designed for rapid revision, grade-focused understanding and question-led teaching.
PhysicalA*
Atomic structure & amount of substance
Mass spec, moles, equations, titration
Clinical / exam questions → Multi-step mole/titration questionsPhysicalA*
Bonding, energetics & kinetics
Shapes, polarity, enthalpy, rates, mechanisms
Clinical / exam questions → Explain rate changes and calculate enthalpyPhysicalA*
Equilibria, acids & thermodynamics
Kc, pH, buffers, entropy, Gibbs
Clinical / exam questions → Predict feasibility and equilibrium shiftsInorganicA*
Periodicity, Group 2, Group 7
Trends, reactions, redox, displacement
Clinical / exam questions → Explain trends using structure and charge densityInorganicA*
Transition metals & aqueous ions
Complexes, ligand substitution, colours, redox
Clinical / exam questions → Predict complex ion reactionsOrganicA*
Mechanisms & synthesis
Alkanes, alkenes, haloalkanes, alcohols, carbonyls
Clinical / exam questions → Draw mechanisms and synthetic routesOrganicA*
Aromatics, amines, polymers
Benzene, phenols, amines, condensation polymers
Clinical / exam questions → Compare electrophilic substitution/additionOrganicA*
Analysis
NMR, IR, mass spec, chromatography
Clinical / exam questions → Identify compounds from spectra
Question bank link: Topic-specific questions are mapped to each note pack. Full question bank coming next.
Medical School OSCE
Highest-yield map designed for rapid revision, grade-focused understanding and question-led teaching.
HistoryDistinction
Chest pain
ACS, PE, dissection, pneumothorax, GI causes
Clinical / exam questions → Red flags and focused differentialsHistoryDistinction
Breathlessness
Asthma/COPD, PE, pneumonia, heart failure, pneumothorax
Clinical / exam questions → Safe focused respiratory/cardiac historyExaminationDistinction
Cardiovascular exam
Inspection, pulse, JVP, precordium, auscultation, oedema
Clinical / exam questions → Present findings and differentialsExaminationDistinction
Respiratory exam
Work of breathing, chest expansion, percussion, auscultation
Clinical / exam questions → Identify consolidation/effusion/pneumothorax patternsCommunicationDistinction
Explaining diagnosis
Chunking, checking understanding, ICE, safety-net
Clinical / exam questions → Explain asthma/diabetes/hypertension clearlyAcuteDistinction
ABCDE assessment
Airway, breathing, circulation, disability, exposure
Clinical / exam questions → Prioritise immediate threatsProceduresPass/Distinction
Cannulation / venepuncture
Consent, asepsis, technique, complications
Clinical / exam questions → Verbalise safety and aftercarePrescribingPass/Distinction
Safe prescription
Allergies, dose, route, interactions, monitoring
Clinical / exam questions → Identify prescribing errors
Question bank link: Topic-specific questions are mapped to each note pack. Full question bank coming next.
MRCP Part 1
Highest-yield map designed for rapid revision, grade-focused understanding and question-led teaching.
MedicineHigh-yield
Cardiology
ACS, arrhythmias, heart failure, murmurs, ECGs
Clinical / exam questions → Best-of-five ECG/management questionsMedicineHigh-yield
Respiratory
Asthma/COPD, ILD, PE, pneumonia, pleural disease
Clinical / exam questions → ABG and CXR interpretationMedicineHigh-yield
Gastroenterology
GI bleed, IBD, liver disease, pancreatitis
Clinical / exam questions → Emergency management and diagnostic testsMedicineHigh-yield
Renal
AKI, CKD, electrolytes, nephritic/nephrotic, acid-base
Clinical / exam questions → Hyperkalaemia and ABG questionsMedicineHigh-yield
Endocrinology
Diabetes, thyroid, adrenal, pituitary, calcium
Clinical / exam questions → Emergency endocrine scenariosMedicineHigh-yield
Neurology
Stroke, seizures, headache, neuropathy, movement disorders
Clinical / exam questions → Localisation and acute treatmentMedicineHigh-yield
Infection
Sepsis, antibiotics, HIV, TB, tropical medicine
Clinical / exam questions → Empirical antibiotic choicesMedicineHigh-yield
Haem/Onc
Anaemia, clotting, transfusion, malignancy emergencies
Clinical / exam questions → Interpret FBC/coagulation patternsMedicineHigh-yield
Rheumatology
Inflammatory arthritis, vasculitis, CTD, crystals
Clinical / exam questions → Autoantibodies and treatmentMedicineHigh-yield
Clinical pharmacology/statistics
Toxicology, adverse effects, sensitivity/specificity, NNT
Clinical / exam questions → Calculations and drug safety
Question bank link: Topic-specific questions are mapped to each note pack. Full question bank coming next.